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KMID : 1103720110650050461
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Journal of the Korean Society of Radiology
2011 Volume.65 No. 5 p.461 ~ p.464
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Magnetic Resonance Finding of Acute Marchiafava-Bignami Disease with Diffuse Involvement: A Case Report
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Heo Young-Jin
Jeong Hae-Woong
In Hyun-Sin
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Abstract
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Marchiafava-Bignami disease (MBD) is a rare toxic disorder strongly associated with chronic alcoholism (1-3, 6, 7). It is characterized by progressive demyelination and necrosis of the corpus callosum. The process may extend to neighboring white matter and subcortical regions. We report a case of MBD in which fluid-attenuated inversion recovery and diffusion-weighted imaging revealed symmetrical hyperintense lesions with diffuse involvement of the corpus callosum, white matter, corticospinal tract, internal capsule, and middle cerebellar peduncle (3, 4, 8).
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KEYWORD
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Marchiafava-Bignami Disease , Corpus Callosum , Diffusion-Weighted Imaging
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